Company Overview
Welcome to the future of sample preparation！
Company Name
Extraction Technologies Japan Co., Ltd.
Hereinafter referred to as ETJ.
ETJ was established in 2024 to introduce EME, an innovative extraction technologies in analytical chemistry and related products developed by ETN (Extraction Technologies Norway), to analytical laboratories throughout Asia and Oceania, including Japan. We are an independent Japanese company with the exclusive rights from ETN to distribute EME products in the region.
Location
596-29 Yurashuku, Hokuei-cho, Tohaku-gun, Tottori, Japan
Contact
E-mail：info@etj-eme.com
URL:etj-eme.com/en
Main Banks
San-in Godo Bank, Ltd
Capital stock
5,000,000 JPY
Establishment
March 2024
Team Members
CEO:
Kazuyuki Takama
＜Career＞
Graduated from Department of Molecular Biology, Saitama University
M.S. in Biotechnology, Flinders University
Research Themes: Bioengineering of active substances using plant cell cultures
Career in Functional food development, development of scientific instruments and consumables, mail-order sales operation, marketing and sales, fresh food business operation
Senior Sales Advisor:
Atsushi Tsunomura
Scientific Advisor:
Takashi Ohnuki
Advisory Tax Accountant:
Teruaki Minemura
Our business
- R&D, manufacturing and sales of scientific instruments and related products
- Export, import and sales of analytical instruments and related products
- Education and seminar management for science and technology
- Consulting for related technologies, products and services
- All operations related to the above
Management Philosophy
Contribute to society while building win-win relationships with the people and companies involved.
Our Mission
Our mission is:
- To find customers in the Asia & Pacific region who are facing problems in the pretreatment process (compound extraction) of chemical analysis and to introduce EME as a solution, and to make them free from the stress of pretreatment.
- To collect testimonies of “EME users” and share them with other users and potential users.
- To contribute to the SDGs by reducing the use of organic solvents in the compound extraction process by 99% and to promote green chemistry.
To register as a member, click here.
Strength of ETJ
ETJ has three strong points.
The first is our strong relationship with ETN. In recognition of our longstanding contribution to the commercialization of the product, ETJ has been granted the exclusive rights to market the products in the Asia-Pacific region, including Japan.
The second is our ability to develop new products. We try to solve challenges in extraction technologies with scientific and free ideas.
The third is people. Each member of the team is highly qualified for success.
Message
Welcome to the future of sample preparation
Thank you for your interest in EME which is the innovative compound extraction technology.
It has been several years since I joined the project to commercialize EME and I am pleased to finally be able to offer you EME products. These are based on patented and innovative compound extraction technology invented by Prof. Stig and his colleagues at the University of Oslo and commercialized by Dr. Roger at ETN. This technology and product is an excellent solution to the challenges that have been standing in the way of the pretreatment step of chemical analysis.
It is exciting to imagine how much impact this new extraction technology and product will have on analytical chemistry in the future.
Looking back, around May of one year, President Roger of ETN, whom I had met during my overseas sales period and had become a friend through my hobby of weight training, approached me about cooperating in the development. At that time, it was just an off-season for the fresh food business I was operating, and I was happy that my friend asked me to help, so I went to Norway, hoping to be of some help. Then, I first learned about the extraction principle of EME and its merits, and when I saw the experimental data, I intuitively thought that this would revolutionize the field of chemical analysis, and I worked enthusiastically with Roger and the researchers to develop the product. In recognition of my contribution, we have been entrusted with the responsibility of selling EME in Japan and the Asia-Pacific region. With a strong sense of mission, we will continue our corporate activities with the intention of introducing EME to all chemical analysis laboratories in the regions where we are in charge of sales.
Can EME revolutionize chemical analysis?
Experimental data from EMEs suggest a possible paradigm shift in pretreatment.
In the analytical field, the advent of high-resolution mass spectrometers has enabled qualitative and quantitative analysis of analytes with higher precision than ever before.
However, the “process of sample preparation: sample cleanup, extraction, concentration, and redissolution” before analysis with the instruments presents universal problems (labor, cost, labor required to obtain uniform homogenization, cumbersome concentration process, sample loss due to sudden boiling, adhesion of sample to container during concentration and solidification, labor required for redissolution, multiple container changes). In addition, there have been following problems: sample loss risk, decomposition of analytes, temperature setting during concentration, residues of foreign components, matrix effects, use of large amounts of organic solvents, contamination of expensive analytical equipment, maintenance costs, downtime, delays in analytical operations, and variations in extraction techniques among personnel.
Although individual solutions have been researched and offered to these issues, there are still no means or products that can comprehensively solve these problems.
If there were a technology or product that could solve these multiple issues in a concise and comprehensive manner, it would be truly revolutionary.
EME is exactly that technology, and the ETN-12 EME, which commercializes it, brings a paradigm shift to the analytical field!
ETJ will continue to build a network to introduce EME products to all chemical analysis laboratories in Japan and the Asia-Pacific region with a sense of urgency, listen to users’ voices, and contribute to the development of extraction technologies together with ETN.
We will continue to update information on product presentations, exhibitions, conferences, and EME applications as needed.
I believe that EME will have an impact equivalent to a meteorite, rather than a stone in the field of analysis, because the principle itself is innovative and rational, and it also solves the problems that existing principles have had in a single blow and in a single step.
Where EMEs can best demonstrate their performance is in the extraction of compounds from biological samples that contain large amounts of complex matrix components.
The dirtier the sample, the better the EME performance!
For example, let’s say that during drug development, blood samples are analyzed to determine how a drug administered to animals or tissues is metabolized.
＜Removal of matrix＞
In this case, blood cannot be analyzed by mass spectrometer without pretreatment. This is because blood contains a large amount of proteins and phospholipids as well as red blood cells and platelets, which must be removed by pretreatment or else the expensive mass spectrometer will be contaminated. In existing methods, blood is first centrifuged to precipitate out the solids, the serum is dispensed into a separate container, and the proteins and phospholipids are removed using organic solvents. However, organic solvents are considered to be harmful to the human body and the environment, and there is growing momentum in the field of green chemistry to reduce the use of organic solvents as much as possible.
After proteins and phospholipids are removed, the vessel is replaced and compound extraction is performed. The mainstream compound extraction techniques used for many years in the field of chemical analysis were liquid-liquid extraction (LLE), which uses a large amount of organic solvent, and solid phase extraction (SPE), which utilizes an organic solvent and adsorbent of various polymeric compounds to extract analytes.
The basic principle of both extraction methods relies on the chemical interactions (intermolecular forces, hydrogen bonds, hydrophobicity, hydrophilicity, etc.) between the organic solvent or adsorbent used and the analyte. Organic solvents are also used in this step.
EME, on the other hand, utilizes electricity to extract ionized compounds. Again, using the power of electricity to extract ionized compounds is a very good principle. This is because ionized compounds in solution are either positively or negatively charged or bipolar, and are therefore susceptible (or susceptible) to the influence of electricity. Therefore, it makes sense in principle to utilize the power of electricity to extract ionized compounds.
Compound extraction is widely recognized as an important pretreatment step in various chemical analyses because of its impact on analytical accuracy. At the same time, however, it is also recognized as a bottleneck in analysis, and global companies offer specialized products for compound extraction. However, multiple challenges still remain (e.g., amount of organic solvents used, labor, matrix effects, etc.).
The solution to this problem is our EME technology and standardized products that make it easy to use in the laboratory. We see the advent of EME as a paradigm shift in the history of analytical science, a technology that will appear in chemistry textbooks in the future, and an indispensable tool that will be introduced in chemical analysis laboratories around the world.
ETJ will contribute to society by providing innovative products and new applications developed by ETN. ETJ will also provide feedback to ETN on customer needs obtained from its corporate activities, and will further strive for further technological innovation.
Our website will be updated with the latest applications using EME. If you would like to see updates immediately, we recommend you to register as a member.
